Vyvanse Vs Adderall - Differences, Which is Better?
Adderall is a much older drug that got its approval around 1996 from FDA. Later a supposedly improved version, Vyvanse, came around 2007.
Doctors will often prescribe one of these drugs for treating Attention Deficit Hyperactivity Disorder (ADHD). Since they belong to the same family of drugs, they tend to show similar symptoms and side effects. As a result, people often wonder if they are the same or can be used alternatively for other conditions.
Adderall and Vyvanse work as central nervous system stimulants. The primary action area is the brain. While they both come from the same component Amphetamine, there is some difference in their composition and how they affect the body. These drugs, if taken in the right doses, can significantly enhance brain activity. But it shouldn’t be obtained without prescription due to several negative consequences.
Composition Difference and Dosage
Adderall- It is a mixture of salts of amphetamine and
dextroamphetamine. Dextroamphetamine is nothing but a dextral isomer of amphetamine. Adderall has a molecular formula of C9H13N. It comes in either tablets or Extended Release Capsule, Adderall XR. The capsule contains beads that contain the drug.
Doses: The tablet form comes in dosage varying from 5mg, 7.5mg, and 10mg to 30mg. It lasts for four hours. The XR form comes in dosage of 5mg, 10mg, 15mg till 30mg. It can last between 8 to 12 hours, varying with dosage.
Vyvanse is a combination of Lisdexamfetamine dimesylate with the molecular formula, C15H25N3O•(CH4O3S)2. Vyvanse is a trading name for the same.
Also, it is packed with some inactive ingredients for more stability and efficiency. Some of them are microcrystalline cellulose, magnesium stearate, and croscarmellose sodium.
Doses: They come in capsules of different doses, 20 mg, 30 mg, 50 mg, and 70 mg.
Mechanism Of Release
Adderall and Adderall XR have different mechanisms of release. One first one releases instantly as it enters the body. However, its effects aren’t long-lasting so, one needs to take them multiple times in a day. Adderall XR dissolution takes time. It slowly releases active ingredients in the body. So. Having it just once a day would be sufficient.
The Stimulant is inactive and protected by a compound called lysine. If the body can absorb the lysine, the stimulant is released. The Lisdexamfetamine has to convert to dextroamphetamine to activate the Prodrug. So this extra process takes up some time to show any results, including the side effects. The medicine comes in a delayed-release capsule. It can be effective for up to 13-14 hours.
Do Vyvanse and Adderall have Similar Effects On the body?
Both are stimulants that interfere with the brain neurotransmitter chemicals norepinephrine and dopamine. But they do not affect likewise. So the way we can understand that is they show different side effects.
Both being stimulants will show some common side effects such as:
· Dryness in mouth
· Nausea and dizziness
· Stomach upset
· Irregular sleep
· Mood swings
· Skin problems like rashes, hives
· Weight loss
· Low blood circulation in toes and fingers
In severe cases, these drugs may also cause seizures, hallucinations, coma, heart attack.
Side-effects specific to Adderall
· Excessive Sweating
· Muscle Stiffness
Side-effects specific to Vyvanse
· Increased heart rate
· Feeling jittery
These medicines should be avoided by pregnant women or breastfeeding women as they may cause premature birth. Also, in children, it causes a slowdown of growth.
Also, these medicines can promote addictive tendencies. Overdose or misuse may cause withdrawal syndromes.
Despite these drawbacks, Adderall and Vyvanse have many benefits like increased focus and decrease impulsiveness. Vyvanse treats BED in children. They both come at different prices. It would be hard to say which performs better. It will only depend on how it’s affecting an individual.